New research suggests that feeding fresh, minimally processed food can shift senior dogs’ metabolism-supporting wellbeing and longevity.

Our mission at Happy Hounds has always been to help dogs live healthier, happier lives. As dogs age, their nutritional needs evolve - and so does our understanding of what truly supports their health. A newly published study from Cornell University (in collaboration with The Farmer’s Dog) offers fresh insights into how diet can influence the ageing process at the metabolic level. Let’s explore what they found, why it matters, and how you can apply the learning to support your senior canine companions.

What Did the Study Do?

The research team recruited 22 senior Alaskan sled dogs and assigned them to a diet of fresh, human-grade, minimally processed food versus standard kibble. Over the course of one year, they monitored metabolomic profiles - essentially looking at hundreds of small molecules in the dogs’ blood to understand metabolic pathways and ageing markers. PetfoodIndustry+2MDPI+2
What makes this study particularly compelling is that the changes happened quickly (within about one month) and lasted through the year. PetfoodIndustry+1

Key Findings

• Reduced Advanced Glycation End Products (AGEs): Dogs on the fresh diet had lower levels of AGEs - compounds that form when proteins or fats combine with sugars in the bloodstream, and which are linked to ageing and chronic disease. PetfoodIndustry+1
• Improved Antioxidant Biomarkers:The fresh-fed group showed higher levels of ergothioneine, carnosine and anserine, metabolites known for antioxidant properties. This suggests better defence against oxidative stress - one of the drivers of ageing. PetfoodIndustry
• Better Metabolic Efficiency & Fat Utilisation: There were elevated levels of branched-chain amino acids (leucine, isoleucine, valine) and long-chain omega-3 fatty acids (ALA, EPA, DPA, DHA). The dogs also had elevated ketone body (3-hydroxybutyrate), indicating increased fat utilisation. At the same time, malonate (marker of fatty acid synthesis) was decreased. These collectively suggest a more efficient, healthier metabolism. MDPI+1
• Rapid & Sustained Impact: According to Dr. Joseph Wakshlag (one of the lead nutritionists in the study): “the magnitude and consistency of the metabolic impacts … were quick, sustained and striking.” PR Newswire+1

Why It Matters for Senior Dogs

• As dogs age, metabolism slows, oxidative damage accumulates, and resiliency (muscle, neurological, immune) tends to decline. This study provides evidence that diet - specifically the quality and processing level of food - can intervene in these pathways.
• For every dog owner or professional working with senior dogs, it means that choice of food is more than just palatability or marketing - it’s influencing fundamental biology.
  

For us at Happy Hounds, this research is a welcome affirmation of what we’ve known intuitively: that senior dogs deserve more than “just age-appropriate kibble”. They deserve a diet that helps protect their metabolism, supports their antioxidant defence, and gives them the best chance of thriving in their later years. Always remember that diet is one piece of ageing. Exercise, veterinary care, genetics, environment all play roles. This research also reinforces our commitment to fresh, minimally processed food for all dogs!